Hyperpigmentation associated with oxprenolol administration.

Tongue hyperpigmentation associated with chemotherapy

W e demonstrate a new hyperpigmentation on the tongue of a 68-year-old female patient who was diagnosed with stage IIA infiltrating ductal carcinoma of the left breast who underwent modified radical mastectomy followed by a triple chemotherapy regimen which consisted of doxorubicin, docetaxel, and cyclophosphamide. The patient developed the tongue hyperpigmentation a few weeks after the initiat...

Chemotherapy-associated supravenous hyperpigmentation.

Amlodipine associated hyperpigmentation.

Amlodipine is a potent peripheral and coronary vasodilator with high selectivity for vascular smooth muscle, and is widely used in mild to moderate hypertension, chronic stable angina and vasospastic angina. Its most prevalent side effects are peripheral edema, flushing and headache. Cutaneous adverse reactions associated with amlodipine have been rarely reported. Herein, a male patient is desc...

Reversible Facial Hyperpigmentation Associated With Vitamin B12 Deficiency.

Vitamin B12 (cobalamin) deficiency is common in developing countries. Its dermatologic manifestations include hair and nail changes and glossitis. Cases of generalized hyperpigmentation associated with vitamin B12 deficiency have rarely been reported. Localized hyperpigmentation is less frequently described, affecting palms, soles, and flexural areas. We report a rare case of reversible melasma...

Hyperpigmentation of tongue associated with hepatitis C treatment.

A 55-year-old white woman receiving peginterferon alfa2a (180 mg) and ribavirin (1200 mg) combination therapy for hepatitis C virus (HCV; genotype 1b) infection complained of a burning sensation and discomfort in her tongue in the second month, and tongue hyperpigmentation in the fourth month of the therapy. Physical examination revealed hyperpigmentation on the lateral and dorsal parts of the ...